The Natural History of Factor VIII : C Inhibitors in Patients With Hemophilia A : A National Cooperative Study . II .
نویسندگان
چکیده
During a 4-year multicenter cooperative study of acquired factor VIII inhibitors in persons with hemophilia A. new inhibitors were detected in 31 of 1 .306 patients who entered the study without an inhibitor or the history of an inhibitor. The incidence of new inhibitors was eight per 1 .000 patient-years of observation. The factor Vlll:C level before inhibitor development was 0.03 U/mi in 29 mdividuals and 0.06 U/mi and 0.07 U/mi in the remaining two. Factor Vlll:Ag levels were measured in 27 individuals and were < 0.03 U/mi in 23 and 0.05 to 0.1 1 U/mi in the remaining four. Maximum inhibitor levels ranged from 1.0
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Detection of Factor VIII Inhibitors in Hemophilia A Patients
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متن کاملThe Natural History of Factor VIII : C Inhibitors in Patients With Hemophilia A : A National Cooperative Study . II . Observations
During a 4-year multicenter cooperative study of acquired factor VIII inhibitors in persons with hemophilia A. new inhibitors were detected in 31 of 1 .306 patients who entered the study without an inhibitor or the history of an inhibitor. The incidence of new inhibitors was eight per 1 .000 patient-years of observation. The factor Vlll:C level before inhibitor development was 0.03 U/mi in 29 m...
متن کاملThe Natural History of Factor VIII : C Inhibitors in Patients With Hemophilia A : A National Cooperative Study
During a 4-year multicenter cooperative study of acquired factor VIII inhibitors in persons with hemophilia A. new inhibitors were detected in 31 of 1 .306 patients who entered the study without an inhibitor or the history of an inhibitor. The incidence of new inhibitors was eight per 1 .000 patient-years of observation. The factor Vlll:C level before inhibitor development was 0.03 U/mi in 29 m...
متن کاملThe natural history of factor VIII:C inhibitors in patients with hemophilia A: a national cooperative study. II. Observations on the initial development of factor VIII:C inhibitors.
During a 4-year multicenter cooperative study of acquired factor VIII inhibitors in persons with hemophilia A, new inhibitors were detected in 31 of 1,306 patients who entered the study without an inhibitor or the history of an inhibitor. The incidence of new inhibitors was eight per 1,000 patient-years of observation. The factor VIII:C level before inhibitor development was less than or equal ...
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